Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy
نویسندگان
چکیده
منابع مشابه
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type.
Slow- and fast-twitch myofibers of adult skeletal muscles express unique sets of muscle-specific genes, and these distinctive programs of gene expression are controlled by variations in motor neuron activity. It is well established that, as a consequence of more frequent neural stimulation, slow fibers maintain higher levels of intracellular free calcium than fast fibers, but the mechanisms by ...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2018
ISSN: 2041-1723
DOI: 10.1038/s41467-018-04038-6